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The loss of glutathione in the HIV + macrophages has been shown to be related to decreased cell defense against Mycobacterium tuberculosis replication [52]

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Finally, we highlight emerging technologies such as single-cell and spatial multi-omics, real-time metabolic imaging and microphysiological systems that can resolve the spatiotemporal heterogeneity of tumour immunometabolism and support more precise immunometabolic interventions